To Compare the Role of Glibenclamide and Pioglitazone Drugs in Type 11 Non- Insulin Dependent Diabetes Mellitus Patients
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Pioglitazone n=27
Glibenclamide n=33
Weight
63.37
+ 2.25
¯
62.7
+ 15.56
¯
Fasting Blood Sugar
172.7
+ 13.32
¯
188.42
+ 12.o5
¯
Random Blood Sugar
285.11
+ 15 .532
¯
284.18
+ 17.07
¯
All Values are expressed in Means± SEM.
FIGURE-1 weight and blood sugar levels observed on baseline (day-o)
In table No shpwing the weight (KG’S) and blood sugar (msg/dl0 levels which is observed on baseline (day-0) in both groups 9group: 1 & group11)
Group: 1 Weight in (Kg’s) mean + SEM) IS 63.37±2.25 Fasting blood sugar 172.7±13.32,and Random
blood sugar 285.11±15.32
Group:11
Weight (KG’s0 (mean +SEM)62.7±1.56 Fasting blood sugar (mg/dl0 188.42±12.05, Random blood sugar is 284.18±17.03.
Figure 2: showing the weight and blood sugar levels observed in base line (day-0) in group: 1 and group 11 weight in 9kg’s) its mean values are 63.37,62.7, Fasting blood sugar in (mg/dl) is 172.71, 188.42 Random blood sugar (mg/dl) is 285.11 &284.18.
TABLE: 2
Peroidic Observation In All Parameters Group1
Goup1(Pioglitazon) n=27
P-value
Day-0
Day-45
Day-90
Day-0to45
Day-45-90
Weight
63.37
±2.25
63.63
±2.26
63.63
±2.23
>0.05
(NS)
>0.05
(NS)
Fasting blood sugar
172.7
±13.32
165.04
±8.98
153.37
±7.59
>0.05
(NS)
0.05
(NS)
Randomblood sugar
285.11
±15.32
279.78
±13.63
255.56
±12.65
>0.05
(NS)
>0.05
(NS)
All values are expressed in Mean±SEM .(NS) Non significant.
TABLE NO:2
Showing the periodic observations in all parameters in group 1 (piogiltazone) (n+27) weight P.value (day 0 to day 45)>0.05 (NS). Fasting blood sugar >0.05 (NS) Random blood sugar >0.05 (NS) P.values day 90 weight >0.05 (N.S), FBS>0.05 (N.S) 7RBS >0.05(N.S) NON SIGNIFICANT
FIGURE:2 Showing the periodic observation in all parameters in group 1 on day0 day 45& day-90.Mean values in weight (Kg) is 63.37,63.26,63.63, fbs (mg/dl) 172.7,165.04,153.37,RBS(mg/dl) 285.11,279.78,255.56.
TABLE NO3
Peroidic Observation in All Parameters Group11
Group 11 (Glibenclamide)
N=33
P-value
Day-0
Day-45
Day-90
Day-0 to 45
Day-45 to 90
Weight
62.7
±1.56
65.64
±2.10
64.55
±1.92
>0.05(NS)
0.05(NS0
Fasting blood sugar
188.42
±12.05
168.45
±10.99
140.06
±5.68
>0.05(NS)
>0.05(S)
Random blood sugar
284.18
±17.03
220.12
±13.39
170.94
±5.80
<0.005 (MS)
0.002(MS0
(s) significant, (MS) moderate significant
All values are expressed in