Tom Howell. Colorectal adenocarcinoma with lung metastases confirmed by biopsy. Already after one month into the Issels Treatment the number and sizes of the metastases in the mediastinum and parenchymal tissue of the lungs decreased. Weight and energy increased. May 2007, a year after the start of the Issels Treatment, his CEA tumor marker is at 1.9 within the normal range. TheIssels Treatment is a comprehensive immunotherapy program that integrates the most effective state-of-the-art technologies, such as advanced cancer vaccines, and other safe and scientifically validated therapies. For more information on the Issels Treatment, please visit www.issels.com or call 1.888.447.7357. Video Rating: 5 / 5