What Is a 5-HT System?
Question by Guess.Who: what is a 5-HT system?
anatomy…chemistry..wise, or whatever. Just curious, i have NO clue what it is though. I’m trying to do research on depression and insomnia and came across the monoamine neurotransmitter “serotonin”, and how it affects both.
Best answer:
Answer by Peter S
Serotonin (5-hydroxytryptamine, 5-HT) is a key mediator in the physiology of mood, vascular function and gastrointestinal motility.
Variety of serotonin receptors – classification:-
Based on biochemical and pharmacological criteria, 5-HT receptors are classified into seven main receptor subtypes, 5-HT1–7. Of major pharmacotherapeutic importance are those designated 5-HT1, 5-HT2, 5-HT4, and 5-HT7, all of which are G-protein-coupled, whereas the 5-HT3 subtype represents a ligand-gated ion channel.
5-HT1 receptors are subdivided into 5-HT1A, 5-HT1B, and 5-HT1D receptors; while 5-HT2 subtypes include 5-HT2A, 5-HT2B, and 5-HT2C
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