Has Anyone Heard of Protracted Withdrawals From Street Drugs and Anti-Depressants?

I was wondering if anyone had any information personal,studies, or anecdotal about protracted withdrawals from street drugs and anti-depressants. What I mean is the idea that drugs get trapped/absorbed into your fat cells while using them. In times of stress, weight loss, etc. these drugs can go back into your bloodstream and cause symptoms like depression, anxiety, and nausea. There are some drug treatment programs that actually use sauna treatments to remove these fat cell drugs. Any thoughts would be greatly appreciated.