Can Anyone Explain in Detail What Drug and Alcohol Abuse Really Do to the Body?

In the past I saw a commercial of an egg being fried with the caption stating: “This is what drugs do to your brain.” Can anyone explain in detail what drug and alcohol abuse really do to the brain and how it effects a persons moral reasoning or any other effect it would have on the brain. How does it effect the entire body? Someone once told me that if you take drugs it could stunt the growth of or shrink your sexual organs, is this true?

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