Is It Better to Use Many Low-Dose Stimulants, or a High Dose of Only One?

Question by capitalism4ever: Is it better to use many low-dose stimulants, or a high dose of only one?
Would a low-dose mixture of methamphetamine, amphetamine, caffeine, cocaine, etc.. or just a lot of one of those be healthier?

I am not a drug user, I’m just curious.

Best answer:

Answer by Jake C
if you spread out the dosage, you’ll be at less of a risk of OD, but I think it would put you at a greater risk for long-term damage.

Keep in mind that amphetamines have a half-life of 11 hours, and caffeine has a half-life of 2; also, consider that it is possible to build a resistance to amphetamines, but the point at which caffeine becomes toxic is very high

Of course, taking them together could cause all sorts of reactions that only a professional pharmacologist could predict.

In my experience, taking caffeine after adderall causes extreme hyperactivity for half an hour; if you put adrenaline into the equation, it impairs judgment slightly. Then there’s a moderate crash that really just feels like normal fatigue, but if you haven’t had anything to eat it becomes much, much worse. The hunger hits you all at once and you feel drained.
This wasn’t in a controlled environment, however, and I also had some prescribed OTC antidepressants, so that might have had an effect.

Without adderall, but with the antidepressants (bupropion if you’re curious), when I had a caffeinated beverage, I felt like hugging everything for a half-hour or so. No noticeable negative effects.

I don’t know anything firsthand about cocaine.

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