What Negative Health Effects Do Drugs Like Hydrocodone and Oxycodone Have on the Body Besides Addiction?

Question by sz z: What negative health effects do drugs like hydrocodone and oxycodone have on the body besides addiction?
Hydrocodone and oxycodone are addictive and people can become dependant upon them. But besides that, what are the negative heath effects? (PS Im talking strictly these medication by themselves, not acetaminophen which is usually combined with these too) Im not asking for side effects either like dizziness, I mean real health effects.

Best answer:

Answer by cat.tuck
my sister has kidney and liver problems associated with her prolonged use

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